Jobs in Structural Biology and Related Fields


CryoEM Staff Scientist


Howard Hughes Medical Institute (HHMI), United States
Application deadline: 23 Nov 2026


The Howard Hughes Medical Institute’s Janelia Research Campus is a pioneering research center in Ashburn, Virginia, where scientists pursue fundamental questions in the life sciences. Our integrated teams of biologists, computational scientists, and tool-builders innovate research practices and technologies to solve biology’s deepest mysteries. HHMI launched Janelia in 2006, establishing an intellectually enriching environment for scientists to do creative, collaborative, hands-on work. We share our methods, results, and tools with the scientific community.

This is a role for someone who wants their scientific judgment to show up in other people's data, not just their own.

The CryoEM Shared Resource at Janelia Research Campus runs four highly configured Titan Krios microscopes, an Aquilos2 and a Hydra cryo FIBSEM, screening electron microscopes, cryo light microscopes, and a full grid-preparation setup, serving structural and cell biologists across the entire HHMI community.


You'll collect high-throughput data for users, take a leading role in the cryoEM side of collaboration projects, and build new methods and protocols when the existing ones fall short. You'll work closely with users and collaborators throughout: planning experiments together, reviewing what the data shows, and figuring out the next step as a peer, not just an instrument operator.

Applicant critera

  • A scientist first. You hold a PhD in a related field and think about an experiment the way a collaborator would, not just an instrument operator.
  • Fluent in the hardware. Comfortable with Linux, bash scripting, and basic Python, enough to troubleshoot a problem rather than just report it.
    Steady inside a moving target. You can hold several concurrent user projects in your head and still make room for whatever breaks that day.
    A real teacher. You enjoy explaining a technique as much as running it, and training someone else doesn't feel like a distraction from your work.

Practical details

Based on site at HHMI's Janelia Research Campus in Ashburn, Virginia. Requires a PhD in a related field. Comes with a competitive total-rewards package, including on-site childcare, campus housing, and shuttle service to and from the Washington, DC metro area.

Find out more or apply here.