Jobs in Structural Biology and Related Fields

Full-Stack Developer / Scientific Software Engineer Position

Biocomputing Unit, Spain

Application deadline: 01 Jun 2026

The Biocomputing Unit and the Instruct Image Processing Center is seeking for a Full-Stack Developer / Scientific Software Engineer.

About Scipion: Scipion is an open-source, workflow-oriented software framework used primarily in Cryo-Electron Microscopy (cryoEM). It integrates various scientific software packages into a unified interface, allowing researchers to execute, track, and share complex image-processing pipelines. Its goal is to ensure reproducibility and provide a seamless experience for processing high-resolution biological data.

About ScipionWeb: ScipionWeb is the modern web-based evolution of this framework. It provides a platform to manage scientific projects and workflows: from project creation and protocol execution to high-level visualization and productivity tools.

Stack: React + TypeScript (Frontend) and FastAPI + Python (Backend).

Role and responsibilities

In the short term, you will:

• Take responsibility for full-stack development of the ScipionWeb interface (UI + API + Integration).
• Learn the backend logic, the Scipion core architecture, and specific scientific domains like SPA (Single Particle Analysis) and Tomography.

In the long term, you will:

• Focus on the Scipion Core and expansion into new scientific domains.
• Maintain and update the ScipionWeb ecosystem to ensure long-term stability.

Requirements

Academic & Language

• Degree: BSc/MSc in Physics, Mathematics, or Software Engineering.
• English: B2 level or equivalent (ability to work in an international environment).

Technical Skills

• Python: 2+ years of experience with Core Python (Standard Library).
• Linux: Solid basic knowledge (Ubuntu is our preferred distribution).
• Version Control: GitHub (PRs, collaborative workflows).
• DevOps/Distribution: Experience with software distribution (PyPI, Conda) and CI/CD (GitHub Actions).

The Tools We Use:

• Frontend: React Router, React Query, MUI, ReactFlow (for diagrams).
• Backend: FastAPI, Pydantic, service-oriented layers.
• Integration: Async workflows (jobs/queues), schema-based forms, and data visualization.

Desirable skills and knowledge:

• Knowledge of Image Processing or cryoEM.
• Experience with 3D visualization (three/react-three-fiber or vtk.js).
• Experience with Docker and Celery.
• A strong eye for API design and complex UI (editors, dashboards, large-scale data).

What We Value

We are looking for someone with a scientific mindset—someone who is not only a great coder but is also curious about how pipelines and HPC (High-Performance Computing) environments work. You should enjoy solving complex logic puzzles and building tools that help scientists discover the building blocks of life.

For full details and how to apply, please visit our website.