A postdoctoral fellowship is available to join the Roll-Mecak lab and advance our work on the structure and mechanism of cytoskeletal regulators. Projects leverage a powerful combination of in vitro reconstitution, high-resolution cryo-EM, and cryo-electron tomography in iPSC derived human neurons to reveal how the cytoskeleton is built, regulated, and remodeled, and build on recent breakthroughs from our lab in visualizing microtubules and their regulators at high-resolution in vitro and in situ (Zehr et al., NSMB 2026; Whittaker et al., MBoC 2026; Chen et al., Nature 2024).
The successful candidate will obtain excellent training in cryo-EM, cell biology and biochemistry. We are looking for Ph.D. graduates with a strong record of accomplishments and expertise in either of these areas: biochemistry and structural biology.
The NIH has an outstanding neuroscience and structural biology community, and the lab has regular access to state-of-the-art resources such as TIRF, iSIM and lattice sheet microscopes, Chameleon, Krios with K3 camera as well as Aquilos 2 cryo-FIB. The NIH provides outstanding career advancement resources, and the postdoctoral fellow will have access to diverse training opportunities on campus.
Bethesda and the surrounding area offer a high-quality of life with great housing, and many indoor and outdoor activity options.
Please send your CV, a one-page research experience summary and contact information of three references to Antonina@nih.gov, and specify “Tubulin Code cryo-EM” in the subject header. The position is available immediately.
