News & Communications

April 2023, IWWD Newsletter: 

 

Temmink JD, Peeters KCMJ, the International Watch & Wait Database (IWWD) Consortium
Watch and wait after neoadjuvant treatment in rectal cancer: comparison of outcomes in patients with and without a complete response at first reassessment in the International Watch & Wait Database(IWWD)

British Journal of Surgery, 2023 March 27; DOI: 10.1093/bjs/znad051


Prata I, Temmink, JD et al. Annals of Case Reports
Submucosal Regrowths after Watch and Wait in Rectal Cancer: A CaseSeries

https://doi.org/10.29011/2574-7754.101180


Fernandez LM, Sao Juliao GP, Renehan AG, et al.
The risk of Distant Metastases in Patients with clinical complete response managed by Watch and Wait after neoadjuvant therapy forrectal cancer: The influence of local regrowth in the International Watch and Wait Database

Diseases of The Colon and Rectum 2023 Jan 1;66(1):41-49. DOI: 10.1097/DCR.0000000000002494



2022

December 2022, IWWD Newsletter

November 2022, IWWD Newsletter

September 2022, IWWD Newsletter

June 2022, IWWD Newsletter

April 2022, IWWD Newsletter

January 2022, IWWD Newsletter

Bahadoer RR, Peeters KCMJ, Beets GL, et al
Watch and wait after a clinical complete response in rectal cancer patients younger than 50 years

British Journal of Surgery, Jan 2022; Vol 109, Issue 1: 114 - 120, https://doi.org/10.1093/bjs/znab372



June 2021, IWWD Newsletter

2021

Al-Najami I, Jones HJ, Dickson EA, et al.
Rectal cancer: Watch-and-wait and continuing the rectal-preserving strategy with local excision for incomplete response or limited regrowth.

Surg Oncol. Apr 3 2021;37:101574. DOI: 10.1016/j.suronc.2021.101574


Bach SP, Gilbert A, Brock K, et al.
Radical surgery versus organ preservation via short-course radiotherapy followed by transanal endoscopic microsurgery for early-stage rectal cancer (TREC): a randomised, open-label feasibility study.

Lancet Gastroenterol Hepatol. Feb 2021;6(2):92-105. DOI: 10.1016/S2468-1253(20)30333-2


Beets GL.
Moving forward with organ preservation in rectal cancer.

Lancet Gastroenterol Hepatol. Feb 2021;6(2):82-83. DOI: 10.1016/S2468-1253(20)30390-3


D'Alimonte L, Bao QR, Spolverato G, et al.
Long-Term Outcomes of Local Excision Following Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer.

Ann Surg Oncol. May 2021;28(5):2801-2808. DOI: 10.1245/s10434-020-09243-6


Faaborg PM, Haas S, Liao D, et al.
Long-term anorectal function in rectal cancer patients treated with chemoradiotherapy and endorectal brachytherapy.

Colorectal Dis. Apr 26 2021. DOI: 10.1111/codi.15692


Fernandez LM, Sao Juliao GP, Figueiredo NL, et al.
Conditional recurrence-free survival of clinical complete responders managed by watch and wait after neoadjuvant chemoradiotherapy for rectal cancer in the International Watch & Wait Database: a retrospective, international, multicentre registry study.

Lancet Oncol. Jan 2021;22(1):43-50. DOI: 10.1016/S1470-2045(20)30557-X


Gambacorta MA, Masciocchi C, Chiloiro G, et al.
Timing to achieve the highest rate of pCR after preoperative radiochemotherapy in rectal cancer: a pooled analysis of 3085 patients from 7 randomized trials.

Radiother Oncol. Jan 2021;154:154-160. DOI: 10.1016/j.radonc.2020.09.026


Gerard JP, Barbet N, Dejean C, et al.
Contact X-ray brachytherapy for rectal cancer: Past, present, and future.

Cancer Radiother. May 26 2021. DOI: 10.1016/j.canrad.2021.04.006


Haak HE, Zmuc J, Lambregts DMJ, et al.
The evaluation of follow-up strategies of watch-and-wait patients with a complete response after neoadjuvant therapy in rectal cancer.

Colorectal Dis. Mar 16 2021; DOI 10.1111/codi.15636


Huisman JF, Schoenaker IJH, Brohet RM, et al.
Avoiding Unnecessary Major Rectal Cancer Surgery by Implementing Structural Restaging and a Watch-and-Wait Strategy After Neoadjuvant Radiochemotherapy.

Ann Surg Oncol. May 2021;28(5):2811-2818. DOI: 10.1245/s10434-020-09192-0


Jankowski M, Pietrzak L, Rupinski M, et al.
Watch-and-wait strategy in rectal cancer: Is there a tumour size limit? Results from two pooled prospective studies.

Radiother Oncol. May 21 2021;160:229-235. DOI: 10.1016/j.radonc.2021.05.014


Jones HJS, Al-Najami I, Baatrup G, Cunningham C.
Local excision after (near) complete response of rectal cancer to neoadjuvant radiation: does it add value?

Int J Colorectal Dis. May 2021;36(5):1017-1022. DOI: 10.1007/s00384-020-03813-6


Meyer VM, Meuzelaar RR, Schoenaker Y, et al.
Delayed Surgery after Neoadjuvant Treatment for Rectal Cancer Does Not Lead to Impaired Quality of Life, Worry for Cancer, or Regret.

Cancers (Basel). Feb 11 2021;13(4) DOI: 10.3390/cancers13040742


Schurink NW, van Kranen SR, Berbee M, et al.
Studying local tumour heterogeneity on MRI and FDG-PET/CT to predict response to neoadjuvant chemoradiotherapy in rectal cancer.

Eur Radiol. Feb 10 2021. DOI: 10.1007/s00330-021-07724-0


Socha J, Bujko K.
Are we already in the era of total neoadjuvant treatment for rectal cancer?

Lancet Oncol. May 2021;22(5):575-577. DOI: 10.1016/S1470-2045(21)00127-3


Santiago I, Barata MJ, Figueiredo N, Pares O, Matos C.
Early conformational changes at tumour bed and long term response after neoadjuvant therapy in locally-advanced rectal cancer.

Eur J Radiol. Jul 2021;140:109742. DOI: 10.1111/codi.15692


Rizzo G, Pafundi DP, Sionne F, et al.
Preoperative chemoradiotherapy affects postoperative outcomes and functional results in patients treated with transanal endoscopic microsurgery for rectal neoplasms.

Tech Coloproctol. Mar 2021;25(3):319-331. DOI: 10.1007/s10151-020-02394-4


Wang QX, Zhang R, Xiao WW, et al.
The watch-and-wait strategy versus surgical resection for rectal cancer patients with a clinical complete response after neoadjuvant chemoradiotherapy.

Radiat Oncol. Jan 19 2021;16(1):16. DOI: 10.1186/s13014-021-01746-0


Witjes CDM, Patel AS, Shenoy A, Boyce S, East JE, Cunningham C.
Oncological outcome after local treatment for early stage rectal cancer.

Surg Endosc. Feb 5 2021. DOI: 10.1007/s00464-021-08308-1


Zaborowski AM, Stakelum A, Winter DC.
Anastomotic leak risk in complete responders to neoadjuvant therapy for rectal cancer: a systematic review.

Int J Colorectal Dis. Apr 2021;36(4):671-676. DOI: 10.1007/s00384-021-03833-w

 

2020 Fernandes; Lancet Oncology

Conditional recurrence-free survival of clinical complete responders managed by watch and wait after neoadjuvant chemoradiotherapy for rectal cancer in the International Watch & Wait Database: a retrospective, international, multicentre registry study Laura M Fernandez MD, Guilherme P São Julião MD, Nuno LFigueiredo PhD, Prof Geerard L Beets PhD, Maxime J M van der Valk,PhD, Renu R Bahadoer MD, Denise E Hilling PhD ElmaMeershoek-Klein Kranenbarg MSc, Annet G H Roodvoets MSc, Prof Andrew G Renehan PhD, Prof Cornelis J H van de Velde PhD, Prof Angelita Habr-Gama PhD, Rodrigo O Perez PhD, the International Watch & Wait Database Consortium*.

Lancet Oncology Available online 11 December 2020
https://authors.elsevier.com/c/1cDtV_XRRTqMXT


2020 van der Sande; Annals of Surgery

Management and Outcome of Local Regrowths in a Watch-and-wait Prospective Cohort for Complete Responses in Rectal Cancer van der Sande, Marit E MD*; Figueiredo, Nuno MD, PhD†; Beets, Geerard L. MD, PhD*,‡ Annals of Surgery 2020
https://journals.lww.com/annalsofsurgery/Abstract/9000/Management_and_Outcome_of_Local_Regrowths_in_a.94685.aspx


2018 van der Valk; Lancet

Long-term outcomes of clinical complete responders after neoadjuvant treatment for rectal cancer in the International Watch & Wait Database (IWWD): an international multicentre registry study Maxime J M van der Valk, Denise E Hilling, Esther Bastiaannet, Elma Meershoek-Klein Kranenbarg, Geerard L Beets, Nuno L Figueiredo, Angelita Habr-Gama, Rodrigo O Perez, Andrew G Renehan, Cornelis J H van de Velde, and the IWWD Consortium* Lancet 2018; 391: 2537–45
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)31078-X/fulltext


2015 Beets; EJSO

Editorial: A new paradigm for rectal cancer: Organ preservation: Introducing the International Watch & Wait Database (IWWD)
G.L.Beets N.L.Figueiredo A.Habr-Gama C.J.H.van de Velde
European Journal of Surgical Oncology (EJSO) Volume 41, Issue 12, December 2015, Pages 1562-1564
https://www.sciencedirect.com/science/article/pii/S074879831500774X


2015 Breugom LO

Is it time for watchful waiting for rectal cancer?
Anne J Breugom Cornelis J H van de Velde
Volume 16, Issue 8, August 2015, Pages 875-876
https://doi.org/10.1016/S1470-2045(15)00015-7