Until its end on July 31 2024, iNEXT-Discovery was a structural biology project funded from the European Commission Horizon 2020 scheme. The partnership involved twenty-six top-notch European structural biology groups and efficiently built on the first iNEXT consortium. iNEXT-Discovery made X-ray-based, NMR, cryo-EM and macromolecular biophysics access services available to external user communities, often researchers without prior experience in the methodology. Through joint research, the partners also developed tools, pipelines and applications, thereby providing integration of structural biology methods and data. During many meetings, theoretical courses, and practical workshops the consrtium reached out to researchers from related fields.