iNEXT-Discovery was a structural biology project funded from the European Commission Horizon 2020 scheme that ended on July 31, 2024. The partnership involved top-notch European academics that efficiently built on the first iNEXT consortium. iNEXT-Discovery made X-rays, NMR, cryo-EM and macromolecular biophysics access services available to external user communities, often researchers without prior experience in the field. Together, the partners developed also methods through joint research, that provide integration of structural biology methods and they reached out to others through meetings, theoretical courses, and practical workshops.