News

The kick-off procedure is now finalized!

Following the two videos introducing iNEXT-Discovery, the virtual kick-off meeting, the virtual General Assembly, and the Scientific Advisory Board (SAB) meeting, for which we have posted previous news, we did not stop! We had virtual meeting also with: The User Panel, with which we discussed procedures to increase user engagement in the project, survey user satisfaction, and find ways to attract new users. A new post-visit questionnaire has been...

First iNEXT-Discovery publication is about fragment screening!

The first publication to come from iNEXT-Discovery is highlighting the continuation between iNEXT and iNEXT-Discovery. It has been published in the "Journal of Biomolecular NMR" and is about "NMR quality control of fragment libraries for screening". The paper describes how the DSI-poised library of fragments, a collection of 782 fragments assembled aiming to facilitate downstream synthesis of ligands with high affinity by fragment ligation, that...

iNEXT-Discovery Scientific Advisory Board meeting

On Thursday June 11th, the iNEXT-Discovery coordination met with the Scientific Advisory Board during a virtual meeting. The major aims of iNEXT-Discovery were shortly reiterated, as well as the role of the SAB in advising us on the course of the project. Several topics that may require attention for optimal project implementation were discussed, as well as how to prepare the consortium for the longer-term.

The virtual kick-off meeting

The kick-off meeting and the General Assembly took place on Thursday 28 May. Short presentations based on the iNEXT-Discovery introduction video (also available from here) were followed by Q&A sessions.  We had 62 on-line participants, and we tried our best to interact. As life is slowly returning to normal, most of our facilities are now open for remote access, and user projects are taking place.

Covid19-NMR: NMR Structural Biology of SARS-CoV-2

The aim of the international project Covid19-NMR is to determine the 3D structures, in particular of all RNAs, and of all proteins of SARS-CoV-2, or exploit existing structures for subsequent search of drugs guided by these structures. The project is coordinated by Prof. Harald Schwalbe who is a member of the iNEXT-Discovery Executive Board, and will be making use of facilities that particate in the iNEXT-Discovery project. The consortium aims to...

Applications for access are now welcome!

While being in turbulent times, we have decided after an inevitable delay due to the current situation, to officially start accepting applications for access to iNEXT-Discovery facilities! We are thus happy to announce to the wider research community this website and welcoming applications. We are posting to the email lists, and social media, so please help us to spread the word! Please do note, that while regardless of current...

New plans for the kick-off meeting

Due to the emerging corona-virus situation, we have decided to cancel the kick-off meeting. Besides being convinced this is the socially responsible choice, it is also the only choice, as the NKI has asked to cancel all international meetings taking place in its premises. The plans to have a kick-off meeting are not abandoned though. We are planning a series of virtual meetings and perhaps a couple of webinars, that we will announce later, after...

iNEXT-Discovery SAB established

We are happy to complete the membership for our Scientific Advisory Board (SAB), who will keep providing feedback and ideas for our future activities throughout the project. Elspeth Garman (Oxford, MX) - Rolf Boelens (Utrecht, iNEXT) - Ilaria Ferlenghi (Italy, GSK) - Kevin Gardner (New York, USA, NMR) - Helen Saibil (London, EM) Elspeth Garman (chair) Rolf Boelens Ilaria Ferlenghi Kevin Gardner Helen Saibil

EC publishes about the iNEXT success

iNEXT was the first program to bring together access to X-ray, NMR and EM facilities in Europe. Marking the closing of the project the EC has published a news article highlighting the iNEXT results. Rolf Boelens, the iNEXT coordinator from Utrecht University in The Netherlands among other things clarified that "iNEXT has received over 900 proposals of which over 700 were approved. The overall impact of the project is illustrated by the more than...

The iNEXT-Discovery grant agreement has been signed

To enable researchers from European institutes to extend innovative structural biology research, the EU has invested 10 million euro to iNEXT-Discovery, through its Horizon 2020 program. The iNEXT-Discovery consortium,  coordinated by Prof. Dr. Anastassis Perrakis from the Netherlands Cancer Institute and Oncode Institute, aims to facilitate the generation of knowledge for the development of new drugs, advanced vaccines, novel biomaterials, engineered...