Access to Structural Biology Facilities

 

!!!! Applications addressing SARS-CoV-2 and/or Covid-19 and mentioning this in the title will be automatically funneled towards rapid review. Our facilities are open for (remote) access and will prioritize such projects if they can be accommodated. Do not worry whether the facility is open or if it has the required safety protocols: just send us your ideas. Click here !!!!

In addition, we may have dedicated Covid-research activities. Please keep an eye on our Covid-research page.

 

iNEXT-Discovery offers a wide range of facility access possibilities and expert support to all European scientists for their translational research in the wider field of structural biology and life sciences, regardless of prior expertise or familiarity with the methods. If you are a cell biologist, a biochemist, a medicinal chemist, working with biomaterials or biotechnology, or work in the food sector, and you have a research question that involves knowledge of the structures of biomolecules and their interactions you can apply for access with iNEXT-Discovery. We specifically encourage researchers with no prior expertise in structural biology to apply for access. Also, all our services are for researchers from academia and industry!

 

The iNEXT-Discovery structural biology facilities are specialized in the following areas:

  • X-ray crystallography and SAXS
  • Nuclear Magnetic Resonance, liquid and solid state, and in-cell (see here our inventory on time-resolved NMR)
  • cryo-Electron Microscopy, single-particle and tomography
  • Macromolecular biophysics

 

If you are considering applying for iNEXT-Discovery access, please continue reading.

 

To apply for access you will need to have the material that you want to study (e.g. a purified protein, or a macromolecular complex, small molecules, DNA, RNA, etc). If you want to study specific proteins or complexes and you do not have the purified macromolecules, please consider contacting our partner Instruct-ERIC!

iNEXT-Discovery will peer-review your proposal for scientific excellence in the context of the goals of the project for enabling translation research. Access provided by iNEXT-Discovery does not involve access fees; also travel, accommodation and shipment of samples can be supported to some extent.

Access to our facilities should be cross-border (i.e. trans-national). All researchers from academia and industry, from Europe and beyond, can ask for access.

We have an on-line submission system for continuous submission and turnover of user proposals. Periodically we will announce specific calls for the health, food, biotechnology, and biomaterials communities. All submitted proposals are peer-reviewed by external referees on scientific quality, and also for technical feasibility by the facility experts. For researchers from industry: we have a process in place in which confidentiality is secured, please contact us in case this is desired for your project.

All access requests should have a clear 'translational component' for bridging structural biology research with applications in biomedical, biotechnological, biomaterial, food or environmental research.

 

!!!! Applications addressing SARS-CoV-2 and/or Covid-19 and mentioning this in the title will be automatically funneled towards rapid review. Our facilities are open for (remote) access and will prioritize such projects if they can be accommodated. Do not worry whether the facility is open or if it has the required safety protocols: just send us your ideas. Click here !!!!

In addition, we may have dedicated Covid-research activities. Please keep an eye on our Covid-research page.

 

 

Our access criteria are summarized as follows

  DO I QUALIFY FOR ...

 

ACADEMIA

INDUSTRY

(SME)

INDUSTRY

(non-SME)

   ... peer-reviewed access?  
AND ...   must I acknowledge iNEXT-Discovery?
AND ...   must I attempt to publish my data?
AND ...   should I publish as Open Access?
   ... "pay-for-service" access?  
   ... workshops and training?  

 

What do I need to start my application?

After registering, you can start your submission. We will start by asking you to choose the "route" that best fits your project, then choose a facility that could be performing it, and then to describe the research background, research objectives, and the translational value of your project. More detailed information will be provided as case-specific help text during your application!

 

Our general Access Guidelines can be found here.

 

For applying for our structural biology access, please follow this link or click the big red button on the top-right ("Apply for Access")! For Covid-related access activities, click here.

 

Some access specifics

  • As an exception, researchers can access our EMBL sites even when these reside in the same country as the facility.
  • Remote access can be tolerated for researchers in the same country as a facility, provided that a similar facility also offers the same kind of access from another country.
  • We also accept access requests from researchers in non-EU countries (up to a certain maximum).
  • To enable peer-reviewed access for researchers from industry, some of our external reviewers have signed Confidentiality Agreements with iNEXT-Discovery.
  • Costs for travel, accommodation and sample shipment can be reimbursed from the facility (always following local regulations).
  • Publications should appear as Open Access (Green / Gold) and acknowledge iNEXT-Discovery:

“This work benefited from access to [the Name of facility] and has been supported by iNEXT-Discovery, project number 871037, funded by the Horizon 2020 program of the European Commission”

 

These are the facilities that provide access in iNEXT-Discovery, most of them can be contacted directly for further information!

 

FACILITY LOCATION TECHNOLOGY CONTACT EMAIL*
ABSL UK, Leeds EM Rebecca Thompson cryoEM@leeds.ac.uk
ALBA ES, Barcelona Xray Maria Jose Simancas useroffice@cells.es
AU DK, Aarhus EM Thomas Boesen thb@mbg.au.dk
CBI FR, Strasbourg EM Marie-Christine Poterszman pmarie@igbmc.fr
CEITEC CZ, Brno NMR, EM Katerina Vagnerova core.facility@ceitec.muni.cz
CIRMMP/CERM IT, Florence NMR   cirmmp@cerm.unifi.it
CSIC ES, Madrid EM Javier Chichon fjchichon@cnb.csic.es
DIAMOND UK, Didcot Xray, EM

EM: Anna rackley

Rest: Nicola Harrington

anna.rackley@diamond.ac.uk

nicola.harrington@diamond.ac.uk

EMBL-GR FR, Grenoble Xray    
EMBL-HD DE, Heidelberg EM Felix Weis cryo-em@embl.de
EMBL-HH DE, Hamburg Xray (MX, SAXS)    
GUF/BMRZ DE, Frankfurt NMR Christian Richter ric@nmr.uni-frankfurt.de
HZB DE, Berlin Xray    
MAX IV SE, Lund Xray    
NeCEN NL, Leiden EM Ludovic Renault l.renault@biology.leidenuniv.nl
NKI NL, Amsterdam Interactions Hans Wienk h.wienk@nki.nl
RALF-NMR FR, Lyon/Grenoble NMR (LY, GR)    
SOLEIL FR, Paris Xray Frédérique Fraissard useroffice@synchrotron-soleil.fr
UU NL, Utrecht NMR Andrei Gurinov a.gurinov@uu.nl

* When contacting the facility, please mention "iNEXT-Discovery" in the subject!