iNEXT-Discovery: Scientific publications

 

 

All publications from iNEXT-Discovery acknowledge the project and appear as Open Access!

 

 

 

101-120  <     >  61-80

 

       

100

Aug 30, 2022

Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding

doi: 10.1093/nar/gkac774

Hyjek-Składanowska M, Anderson BA, Mykhaylyk V, Orr C, Wagner A, Poznański JT, Skowronek K, Seth P, Nowotny M.

Nucleic Acids Research, 2022, gkac774

99

Sep 17, 2022

Comprehensive Fragment Screening of the SARS-CoV-2 Proteome Explores Novel Chemical Space for Drug Development

doi: 10.1002/anie.202205858

Berg H, Wirtz Martin MA, Altincekic N, Alshamleh I, Kaur Bains J, Blechar J, Ceylan B, de Jesus V, Dhamotharan K, Fuks C, Gande SL, Hargittay B, Hohmann KF, Hutchinson MT, Korn SM, Krishnathas R, Kutz F, Linhard V, Matzel T, Meiser N, Niesteruk A, Pyper DJ, Schulte L, Trucks S, Azzaoui K, Blommers MJJ, Gadiya Y, Karki R, Zaliani A, Gribbon P, Almeida MDS, Anobom CD, Bula AL, Buetikofer M, Caruso ÍP, Felli IC, Da Poian AT, de Amorim GC, Fourkiotis NK, Gallo A, Ghosh D, Gomes-Neto F, Gorbatyuk O, Hao B, Kurauskas V, Lecoq L, Li Y, Mebus-Antunes NC, Mompean M, Neves-Martins TC, Ninot-Pedrosa M, Pinheiro AS, Pontoriero L, Pustovalova Y, Riek R, Robertson A, Abi Saad MJ, Treviño MA, Tsika AC, Almeida FCL, Bax A, Henzler-Wildman K, Hoch JC, Jaudzems K, Laurents DV, Orts J, Pieratelli R, Spyroulias GA, Duchardt-Ferner E, Ferner J, Fuertig B, Hengesbach M, Löhr F, Qureshi N, Richter C, Saxena K, Schlundt A, Sreeramulu S, Wacker A, Weigand JE, Wirmer-Bartoschek J, Woehnert J, Schwalbe H.

Angew Chem Int Ed Engl. 2022

98

May 10, 2022

1H-Detected Biomolecular NMR under Fast Magic-Angle Spinning

doi: 10.1021/acs.chemrev.1c00918

Le Marchand T, Schubeis T, Bonaccorsi M, Paluch P, Lalli D, Pell AJ, Andreas LB, Jaudzems K, Stanek J, Pintacuda G.

Chem Rev 2022, 122(10):9943-10018

97

Jul 27, 2022

Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF

doi: 10.1126/sciadv.abo0517

Corbeski I, Guo X, Eckhardt BV, Fasci D, Wiegant W, Graewert MA, Vreeken K, Wienk H, Svergun DI, Heck AJR, van Attikum H, Boelens R, Sixma TK, Mattiroli F, van Ingen H.

Sci Adv. 2022, 8(30):eabo0517

96

Jul 07, 2022

Higher resolution in cryo-EM by the combination of macromolecular prior knowledge and image- processing tools

doi: 10.1107/S2052252522006959

Ramirez-Aportela E, Carazo JM, Sorzano COS.

IUCrJ 2022, 9(5)

95

Aug 11, 2022

Teixobactin kills bacteria by a two-pronged attack on the cell envelope

doi: 10.1038/s41586-022-05019-y

Shukla R, Lavore F, Maity S, Derks MGN, Jones CR, Vermeulen BJA, Melcrová A, Morris MA, Becker LM, Wang X, Kumar R, Medeiros-Silva J, van Beekveld RAM, Bonvin AMJJ, Lorent JH, Lelli M, Nowick JS, MacGillavry HD, Peoples AJ, Spoering AL, Ling LL, Hughes DE, Roos WH, Breukink E, Lewis K, Weingarth M.

Nature 2022, 608(7922):390-396

94

Aug 05, 2022

Toward protein NMR at physiological concentrations by hyperpolarized water-Finding and mapping uncharted conformational spaces

doi: 10.1126/sciadv.abq5179

Epasto LM, Che K, Kozak F, Selimovic A, Kadeřávek P, Kurzbach D.

Science Advances 2022, 8(31):eabq5179.

93

Jul 06, 2022

Binding adaptation of GS-441524 diversifies macro domains and downregulate SARS-CoV-2 de-MARylation capacity

doi: 10.1016/j.jmb.2022.167720

Tsika AC, Gallo A, Fourkiotis NK, Argyriou AI, Sreeramulu S, Löhr F, Rogov VV, Richter C, Linhard V, Gande SL, Altincekic  N, Krishnathas R, Elamri I, Schwalbe H, Wollenhaupt J, Weiss MS, Spyroulias GA.

Journal of Molecular Biology (2022),

92

Jun 30, 2022

Identification and Characterization of an RRM‐Containing, RNA Binding Protein in Acinetobacter baumannii

doi: 10.3390/biom12070922

Ciani C, Pérez‐Ràfols A, Bonomo I, Micaelli M, Esposito A, Zucal C, Belli R, D’Agostino VG, Bianconi I, Calderone V, Cerofolini L, Massidda O, Whalen MB, Fragai M, Provenzani A.

Biomolecules 2022, 12, 922.

91

Jun 13, 2022

Heteronuclear decoupling with Rotor-Synchronized Phase-Alternated Cycles

doi: 10.1063/5.0098135

Simion A, Schubeis T, Tanguy Le Marchand T, Vasilescu M, Pintacuda G, Lesage A, Filip C

J. Chem. Phys. (2022), in press

90

Jan 18, 2022

The Extended Hadamard Transform: Sensitivity-Enhanced NMR Experiments Among Labile and Non-Labile 1Hs of SARS-CoV-2-derived RNAs

doi: 10.1002/cphc.202100704

Kim J, Novakovic M, Jayanthi S, Lupulescu A, Kupče Ē, Grün JT, Mertinkus K, Oxenfarth A, Schwalbe H, Frydman L.

ChemPhysChem 2022, 23, e202100704

89

Mar 25, 2022

Epitope Mapping and Binding Assessment by Solid-State NMR Provide a Way for the Development of Biologics under the Quality by Design Paradigm

doi: 10.1021/jacs.2c03232

Rizzo D, Cerofolini L, Giuntini S, Iozzino L, Pergola C, Sacco F,  Palmese A, Ravera E, Luchinat C, Baroni F, Fragai M.

J. Am. Chem. Soc. 2022

88

May 27, 2022

Whole-proteome structures shed new light on posttranslational modifications

doi: 10.1371/journal.pbio.3001673

Joosten RP, Agirre J.

PLoS Biol 2022, 20(5):e3001673

87

Apr 29, 2022

Discovery of novel druggable pockets on polyomavirus VP1 through crystallographic fragment-based screening to develop capsid assembly inhibitors

doi: 10.1039/d2cb00052k

Osipov EM, Munawar AH, Beelen S, Fearon D, Douangamath A, Wild C, Weeks SD, Van Aerschot A, Von Delft F, Strelkov SV.

RCS Chemical Biology 2022, Apr 29

86

Apr 26, 2022

Backbone and side chain resonance assignment of the intrinsically disordered human DBNDD1 protein.

doi: 10.1007/s12104-022-10086-3

Wiedemann C, Obika KB, Liebscher S, Jirschitzka J, Ohlenschläger O, Bordusa F.

Biomol NMR Assign. 2022, Apr 26

85

Apr 13, 2022

Beta and Gamma Amino Acid-Substituted Benzenesulfonamides as Inhibitors of Human Carbonic Anhydrases.

doi: 10.3390/ph15040477

Balandis B, Šimkūnas T, Paketurytė-Latvė V, Michailovienė V, Mickevičiūtė A, Manakova E, Gražuli S, Belyakov S, Kairys V, Mickevičius V, Zubrienė A, Matulis D.

Pharmaceuticals 2022, 15, 477

84

Apr 04, 2022

Image processing tools for the validation of CryoEM maps.

doi: 10.1039/D2FD00059H

Sorzano COS, Vilas JL, Ramírez-Aportela E, Krieger J, del Hoyo D, Herreros D, Fernandez-Giménez E, Marchán D, Macías JR, Sánchez I, del Caño L, Fonseca-Reyna Y, Conesa P, García-Mena A, Burguet J, García Condado J, Méndez García J, Martínez M, Muñoz-Barrutia A, Marabini R, Vargas J, Carazo JM.

Faraday Discuss., 2022, Accepted Manuscript

 83

Apr 09, 2022 

Oxidation of the Mycobacterium tuberculosis key virulence factor Protein Tyrosine Phosphatase A (MptpA) reduces its phosphatase activity.

doi: 10.1002/1873-3468.14348

Niesteruk A, Sreeramulu S, Jonker HRA, Richter C, Schwalbe H.

FEBS Lett. 2022

 82

Feb 18, 2022 

On bias, variance, overfitting, gold standard and consensus in single-particle analysis by cryo-electron microscopy.

doi: 10.1107/S2059798322001978

Sorzano COS, Jiménez-Moreno A, Maluenda D, Martínez M, Ramírez-Aportela E, Krieger J, Melero R, Cuervo A, Conesa J, Filipovic J, Conesa P, Del Caño L, Fonseca YC, Jiménez-de la Morena J, Losana P, Sánchez-García R, Strelak D, Fernández-Giménez E, de Isidro-Gómez FP, Herreros D, Vilas JL, Marabini R, Carazo JM.

Acta Crystallogr D Struct Biol. 2022 78(4):410-423

81

Feb 25, 2022

The BAF A12T mutation reduces BAF affinity to lamin A/C, preventing its recruitment to nuclear ruptures in Nestor Guillermo Progeria Syndrome cells.

doi: 10.1101/2022.02.25.481780

Janssen AFJ, Marcelot A, Breusegem SY, Legrand P, Zinn-Justin S, Larrieu D

bioRxiv 2022.02.25.481780

101-120  <     >  61-80