200

A multi-scale numerical approach to study monoclonal antibodies in solution

doi: 10.1063/5.0186642

Polimeni M, Zaccarelli E, Gulotta A, Lund M, Stradner A, Schurtenberger P.

APL Bioengineering

199

Structural basis for activation and mechanism of the bacterial hexameric motors RadA and ComM in DNA branch migration during homologous recombination

doi: 10.1101/2024.02.15.580443

Talachia Rosa L, Vernhes E, Soulet AL, Polard P, Fronzes R.

bioRxiv preprint

198

Ultrastructure of macromolecular assemblies contributing to bacterial spore resistance revealed by in situ cryo-electron tomography

doi: 10.1038/s41467-024-45770-6

Bauda E, Gallet B, Moravcova J, Effantin G, Chan H, Novacek J, Jouneau PH, Rodrigues CDA, Schoehn G, Moriscot C, Morlot C.

Nat Commun. 2024 Feb 14;15(1):1376

197

Design, Quality and Validation of the EU-OPENSCREEN Fragment Library Poised to a High-Throughput Screening Collection

doi: 10.1039/d3md00724c

Jalencas X, Berg H, Espeland LO, Sreeramulu S, Kinnen F, Richter C, Georgiou C, Yadrykhinsky V, Specker E, Jaudzems K, Mileti T, Harmel R, Gribbon P, Schwalbe H, Brenk R, Jirgensons A, Zaliani A, Mestres J.

RSC Med. Chem., 2024

196

Identification of potential aggregation hotspots on Aβ42 fibrils blocked by the anti-amyloid chaperone-like BRICHOS domain

doi: 10.1038/s41467-024-45192-4

Kumar R, Le Marchand T, Adam L, Bobrovs R, Chen G, Fridmanis J, Kronqvist N, Biverstål H, Jaudzems K, Johansson J, Pintacuda G, Abelein A.

Nat Commun. 2024 Feb 1;15(1):965

195

Biochemical and Structural Characterization of CRH-1, a Carbapenemase from Chromobacterium haemolyticum Related to KPC β-Lactamases

doi: 10.1128/aac.00061-23

Brunetti F, Ghiglione B, Gudeta DD, Gutkind G, Guardabassi L, Klinke S, Power P.

Antimicrob Agents Chemother. 2023 Jul 18;67(7):e0006123

194

Improved detection of magnetic interactions in proteins based on long-lived coherences

doi: 10.21203/rs.3.rs-3694602/v1

Sadet A, Ianc O, Teleanu F, Ciumeică A, Lupulescu A, Vasos P.

Research Square, Version 1

193

Molecular mechanisms and evolutionary robustness of a color switch in proteorhodopsins

doi: 10.1126/sciadv.adj0384

Mao J, Jin X, Shi M, Heidenreich D, Brown LJ, Brown RCD, Lelli M, He X, Glaubitz C.

Sci Adv. 2024 Jan 26;10(4):eadj0384

192

EasyGrid: A versatile platform for automated cryo-EM sample preparation and quality control

doi: 10.1101/2024.01.18.576170

Gemin O, Armijo V, Hons M, Bissardon C, Linares R, Bowler MW, Wolff G, Kovalev K, Babenko A, Salo VT, Schneider S, Rossi C, Lecomte L, Deckers T, Lauzier K, Janocha R, Felisaz F, Sinoir J, Galej WP, Mahamid J, Muller CW, Eustermann S, Mattei S, Cipriani F, Papp G.

bioRxiv preprint

191

Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies

doi: 10.1021/acschembio.3c00720 

Altincekic N, Jores N, Löhr F, Richter C, Ehrhardt C, Blommers MJJ, Berg H, Öztürk S, Gande SL, Linhard V, Orts J, Abi Saad MJ, Bütikofer M, Kaderli J, Karlsson BG, Brath U, Hedenström M, Gröbner G, Sauer UH, Perrakis A, Langer J, Banci L, Cantini F, Fragai M, Grifagni D, Barthel T, Wollenhaupt J, Weiss MS, Robertson A, Bax A, Sreeramulu S, Schwalbe H.

ACS Chem Biol. 2024 Jan 17

190

Ligand-Based Competition Binding by Real-Time 19F NMR in Human Cells

doi: 10.1021/acs.jmedchem.3c01600

Luchinat E, Barbieri L, Davis B, Brough PA, Pennestri M, Banci L.

J Med Chem. 2024

189

Multitasking Pharmacophores Support Cabotegravir-Based Long-Acting HIV Pre-Exposure Prophylaxis (PrEP)

doi: 10.3390/molecules29020376

Wan Z, Shi M, Gong Y, Lucci M, Li J, Zhou J, Yang X-L, Lelli M, He X, Mao J.

Molecules. 2024; 29(2):376

188

TIR domains produce histidine-ADPR conjugates as immune signaling molecules in bacteria

doi: 10.1101/2024.01.03.573942

Sabonis D, Avraham C, Lu A, Herbst E, Silanskas A, Leavitt A, Yirmiya E, Zaremba M, Amitai G, Kranzusch PJ, Sorek R, Tamulaitiene G.

bioRxiv preprint

187

Structural Heterogeneity in a Phototransformable Fluorescent Protein Impacts its Photochemical Properties

doi: 10.1002/advs.202306272

Maity A, Wulffelé J, Ayala I, Favier A, Adam V, Bourgeois D, Brutscher B.

Adv Sci (Weinh). 2023 Dec 25:e2306272

186

Structure of the dopamine D3 receptor bound to a bitopic agonist reveals a new specificity site in an expanded allosteric pocket

doi: 10.21203/rs.3.rs-3433207/v1

Arroyo-Urea S, Nazarova AL, Carrión-Antolí A, Bonifazi A, Battiti FO, Homing Lam J, Hauck Newman A, Katritch V, García-Nafría J.

PREPRINT V1, available at Research Square

185

DNA i-motif levels are overwhelmingly depleted in living human cells: insights from in-cell NMR

doi: 10.21203/rs.3.rs-3734993/v1

Trantirek L, Viskova P, Istvankova E, Rynes J, Dzatko S, Loja T, Lenarcic Zivkovic M, Rigo R, El-Khoury R, Serano I, Damha M, Gonzalez C, Mergny JL, Foldynova-Trantirkova S.

PREPRINT V1, available at Research Square

184

Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1

doi: 10.21203/rs.3.rs-3220888/v1

Düring J, Wolter M, Toplak J, Torres C, Dybkov O, Fokkens TJ, Urlaub H, Steinchen W, Dienemann C, Lorenz S.

PREPRINT V1, available at Research Square

183

Enlarging the scenario of site directed 19F labeling for NMR spectroscopy of biomolecules

doi: 10.1038/s41598-023-49247-2

Vitali V, Torricella F, Massai L, Messori L, Banci L.

Sci Rep. 2023 Dec 12;13(1):22017

182

From isolated polyelectrolytes to star-like assemblies: The role of sequence heterogeneity on the statistical structure of the intrinsically disordered Neurofilament-low tail domain

Kravikass M, Koren G, Saleh OA, Beck R.

https://arxiv.org/pdf/2311.18337.pdf

181

Common transthyretin-derived amyloid fibril structures in patients with hereditary ATTR amyloidosis

doi: 10.1038/s41467-023-43301-3

Steinebrei M, Baur J, Pradhan A, Kupfer N, Wiese S, Hegenbart U, Schönland SO, Schmidt M, Fändrich M.

Nat Commun. 2023 Nov 22;14(1):7623